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Alternative ion channel splicing in mesial temporal lobe epilepsy and Alzheimers disease

genomebiology.com » 2007 » March » 7th » Alternative ion channel splicing in mesial temporal lobe epilepsy and Alzheimers disease

Background: Alternative gene transcript splicing permits a single gene to produce multiple proteins with varied functions. Bioinformatic investigations have identified numerous splice variants, but whether these transcripts are translated to functional proteins and the physiological significance of these alternative proteins are largely unknown. Through direct identification of splice variants … Continue Reading »

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